Dr Katherine Gordon-Smith

Senior Research Fellow in Psychological Medicine

Mood Disorders Research Group

Contact Details

email: k.gordon-smith@worc.ac.uk

Katherine joined the University of Worcester in October 2015 previously working as Postdoctoral Researcher within the Institute of Psychological Medicine and Clinical Neurosciences at Cardiff University and then as a Research Fellow at the University of Birmingham.

She is a senior member of the Mood Disorders Research Group. The broad aims of the group are to investigate genetic and other factors that may contribute to the aetiology of bipolar disorder and other related mood and psychotic illnesses, such as schizoaffective disorder and postpartum psychosis.

She is Chair of the College of Health, Life and Environmental Sciences Research Ethics Committee.

 

Qualifications

 

2008 PhD Psychiatric Genetics - Cardiff University.
2005 Diploma in Research Methods (with distinction) - Cardiff University.
2000 BSc (Combined Hons) Psychology & Biology - Aston University.

Research

She was one of the co-founders of the Bipolar Disorder Research Network (BDRN) , a group of researchers, clinicians and research participants in the UK involved in investigating the underlying causes of bipolar disorder. So far more than 7000 participants have been recruited to BDRN, which is one the largest sample of individuals with bipolar disorder in the world.

Katherine’s particular research interest is co-morbidities in bipolar disorder including migraine and anxiety. She oversees the running of the mood monitoring system True Colours which is currently being offered to BDRN members, in collaboration with colleagues at the University of Oxford.  The system is delivering a vast amount of data to help understand more about how mood symptoms present over time in individuals with bipolar disorder and how they are affected by changes in routines such as sleep.

Katherine works closely with BDRN research champions, research participants with lived experience of bipolar disorder, who provide expert advice and input into the BDRN research programme and True Colours.

Teaching

Katherine has been teaching undergraduate students for the past 15 years. She delivers lectures on mood disorders, research ethics and quantitative research methods across a range of disciplines, including, midwifery, advanced clinical practice and paramedic science and psychology. She supervises a number of undergraduate psychology research projects each year and runs sessions on the postgraduate Researcher Development Programme

Postgraduate supervision

Amy Perry, PhD completed 2019 (Supervisor) Investigating risk factors for postpartum psychosis in bipolar disorder

Emma Tickle, current PhD student (Supervisor) Examining the prevalence, clinical correlates and perceived impact of a borderline personality disorder diagnosis in individuals with bipolar disorder in the UK.

Kim Caldwell, current PhD student (Supervisor) Illness perceptions in people with bipolar disorder

Krista Easton, current PhD student (Supervisor) Autism spectrum conditions in bipolar disorder

Gemma Glenister, current PhD student (Supervisor) Emotional intelligence and bipolar disorder.

Alice Clements, current PhD student (Supervisor) Perinatal mood in men who have bipolar disorder.

Memberships

Bipolar Disorder Research Network

British Psychological Society

International Society of Psychiatric Genetics

International Society for Bipolar Disorders

Publications

SELECTED RECENT PUBLICATIONS
Total to date 92; h-index 40 (January 2021)

Link to Google Scholar profile page:

https://scholar.google.com/citations?hl=en&user=gMdTJjQAAAAJ

2021 selected publications

Perry, A., Gordon-Smith, K., Jones, L., & Jones, I. (2021). Phenomenology, Epidemiology and Aetiology of Postpartum Psychosis: A Review. Brain sciences11(1), E47.

The Bipolar Disorder Working Group of the Psychiatric Genomics Consortium. (2021) Genome-wide association study of over 40,000 bipolar disorder cases provides novel biological insights.  Nature Genetics, in press 

2020 selected publications

Gordon-Smith, K., Saunders, K. E., Savage, J., Craddock, N., Jones, I., & Jones, L. (2020). Have I argued with my family this week?": What questions do those with lived experience choose to monitor their bipolar disorder?. Journal of affective disorders, in press

Saunders, K., Jones, T., Perry, A., Di Florio, A., Craddock, N., Jones, I., Gordon-Smith, K., & Jones, L. (2020). The influence of borderline personality traits on clinical outcomes in bipolar disorder. Bipolar disordersin press.

Gordon-Smith, K., Lewis, K., Vallejo Auñón, F. M., Di Florio, A., Perry, A., Craddock, N., Jones, I., & Jones, L. (2020). Patterns and clinical correlates of lifetime alcohol consumption in women and men with bipolar disorder: Findings from the UK Bipolar Disorder Research Network. Bipolar disorders22(7), 731–738. 

Gordon-Smith K, Perry A, Di Florio A, Forty L, Fraser C, Casanova-Dias M, Warne N, MacDonald T, Craddock N, Jones L and Jones I. Symptom profile of postpartum and non-postpartum manic episodes in bipolar I disorder: a within-subjects study (2020). Psychiatry Research, 284, 112748. 

Perry A, Gordon-Smith K, Di Florio A, Fraser C, Craddock N, Jones L and Jones I. Adverse childhood experiences and postpartum depression in bipolar disorder (2020). Journal of Affective Disorders, 263: 661-666

Marwaha, S., Briley, P. M., Perry, A., Rankin, P., DiFlorio, A., Craddock, N., Jones, I., Broome, M., Gordon-Smith, K., & Jones, L. (2020). Bipolar disorder: a path analysis of 923 people with bipolar I disorder. Psychological medicine50(14), 2346–2354.

Lewis, K., Richards, A., Karlsson, R., Leonenko, G., Jones, S. E., Jones, H. J., Gordon-Smith, K., Forty, L., Escott-Price, V., Owen, M. J., Weedon, M. N., Jones, L., Craddock, N., Jones, I., Landén, M., O'Donovan, M. C., & Di Florio, A. (2020). Comparison of Genetic Liability for Sleep Traits Among Individuals With Bipolar Disorder I or II and Control Participants. JAMA psychiatry77(3), 303–310. 

2019 selected publications

Gordon-Smith, K., Saunders, K., Geddes, J.R., Harrison, P.J., Hinds, C., Craddock, N., Jones, I., Jones, L. Large-scale roll out of electronic longitudinal mood-monitoring for research in affective disorders: Report from the UK bipolar disorder research network (2019). Journal of Affective Disorders, 246: 789–793.

Serra, F., Gordon‐Smith, K., Perry, A., Fraser, C., Di Florio, A., Craddock, N., Jones, I., Jones, L. Agitated depression in bipolar disorder (2019). Bipolar Disorders, 21: 547–555.

Perry A, Gordon-Smith K, Webb I, Fone E, Di Florio A, Craddock N, Jones I and Jones L. Postpartum psychosis in bipolar disorder: no evidence of association with personality traits, cognitive style or affective temperaments (2019). BMC Psychiatry, 19 (1): 395.

The Bipolar Disorder Working Group of the Psychiatric Genomics Consortium. Genome-wide association study identifies 30 loci associated with bipolar disorder (2019). Nature Genetics, 51: 793-803.

2018 selected publications

Gordon-Smith, K., Craddock, N., Green, E., Grozeva, D., Tavadia, S., Jones, L., 2018. Genotype – phenotype correlations in Darier disease : A focus on the neuropsychiatric phenotype (2018). American Journal of Medical Genetics. Part B Neuropsychiatric. Genetics. 177: 717–726.

Di Florio A, Gordon-Smith K, Forty L, Kosorok MR, Fraser C, Perry A, Bethell A, Craddock N, Jones L and Jones I. Stratification of the risk of bipolar disorder recurrences in pregnancy and postpartum (2018). British Journal of Psychiatry, 213(3): 542-547.

Lewis KJS, Di Florio A, Forty L, Gordon-Smith K, Perry A, Cradock N, Jones L and Jones I. Mania triggered by sleep loss and risk of postpartum psychosis in women with bipolar disorder (2018). Journal of Affective Disorders, 225: 624-629

Allardyce, J., Leonenko, G., Hamshere, M., Pardiñas, A. F., Forty, L., Knott, S., Gordon-Smith, K., Porteous, D. J., Haywood, C., Di Florio, A., Jones, L., McIntosh, A. M., Owen, M. J., Holmans, P., Walters, J., Craddock, N., Jones, I., O'Donovan, M. C., & Escott-Price, V. (2018). Association Between Schizophrenia-Related Polygenic Liability and the Occurrence and Level of Mood-Incongruent Psychotic Symptoms in Bipolar Disorder. JAMA psychiatry75(1), 28–35. 

Leonenko, G., Di Florio, A., Allardyce, J., Forty, L., Knott, S., Jones, L., Gordon-Smith, K., Owen, M. J., Jones, I., Walters, J., Craddock, N., O'Donovan, M. C., & Escott-Price, V. (2018). A data-driven investigation of relationships between bipolar psychotic symptoms and schizophrenia genome-wide significant genetic loci. American journal of medical genetics. Part B, Neuropsychiatric genetics,177(4), 468–475. 

Bipolar Disorder Working Group of the Psychiatric Genomics Consortium (2018). Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes. Cell. 173; 1705–1715.

2017 selected publications

Gordon-Smith, K., Jones, L., Forty, L., Craddock, N., Jones, I., 2017. Changes to the Diagnostic Criteria for Bipolar Disorder in DSM-5 Make Little Difference to Lifetime Diagnosis: Findings from the UK BDRN Study. American Journal of Psychiatry, 174: 803.

Lewis, K.S., Gordon-Smith, K., Forty, L., Di Florio, A., Craddock, N., Jones, L., Jones, I., Florio, A. Di, Craddock, N., Jones, L., Jones, I., Di Florio, A., Craddock, N., Jones, L., Jones, I., 2017. Sleep loss as a trigger of mood episodes in bipolar disorder : individual differences based on diagnostic subtype and gender. British Journal of  Psychiatry, 211: 169–174.

Perry A, Gordon-Smith K, Jones L and Jones I. A visual timeline tool for tracking mood and medication perinatally in affective disorders (2017). Archives of Women’s Mental Health, 20(5): 709-710

Green, E. K., Di Florio, A., Forty, L., Gordon-Smith, K., Grozeva, D., Fraser, C., Richards, A. L., Moran, J. L., Purcell, S., Sklar, P., Kirov, G., Owen, M. J., O'Donovan, M. C., Craddock, N., Jones, L., & Jones, I. R. (2017). Genome-wide significant locus for Research Diagnostic Criteria Schizoaffective Disorder Bipolar type. American journal of medical genetics. Part B, Neuropsychiatric genetics,174(8), 767–771. 

Abu-Akel, A., Clark, J., Perry, A., Wood, S. J., Forty, L., Craddock, N., Jones, I., Gordon-Smith, K., & Jones, L. (2017). Autistic and schizotypal traits and global functioning in bipolar I disorder. Journal of affective disorders207, 268–275. 

2016 selected publications

Marwaha, S., Gordon-Smith, K., Broome, M., Briley, P.M.M., Perry, A., Forty, L., Craddock, N., Jones, I., Jones, L., Affective instability, childhood trauma and major affective disorders (2016). Journal of Affective Disorders, 190: 764–771.

Perry A, Gordon-Smith K, Di Florio A, Forty L, Craddock N, Jones L and Jones I. Adverse Childhood Life Events and Postpartum Psychosis in Bipolar Disorder (2016). Journal of Affective Disorders, 205: 69-72

Green, E. K., Rees, E., Walters, J. T., Gordon-Smith, K., Forty, L., Grozeva, D., Moran, J. L., Sklar, P., Ripke, S., Chambert, K. D., Genovese, G., McCarroll, S. A., Jones, I., Jones, L., Owen, M. J., O'Donovan, M. C., Craddock, N., & Kirov, G. (2016). Copy number variation in bipolar disorder. Molecular psychiatry21(1), 89–93.

2015 selected publications

Gordon-Smith K, Forty L, Chan C, Knott S, Jones I, Craddock N, Jones LA. Rapid cycling as a feature of bipolar disorder and comorbid migraine (2015). Journal of Affective Disorders, 175:320-4.

Jones L, Metcalf A, Gordon-Smith K, Forty L, Perry A, Lloyd J, Geddes JR, Goodwin G.M, Jones I, Craddock N and Rogers, RD The prevalence and distribution of gambling problems in bipolar disorder in the United Kingdom (2015). British Journal of Psychiatry 207:328-33.

 Upthegrove, R., Chard, C., Jones, L., Gordon-Smith, K., Forty, L., Jones, I., & Craddock, N. (2015). Adverse childhood events and psychosis in bipolar affective disorder. The British journal of psychiatry, 206(3), 191–197. 

2014 selected publications

Di Florio A, Jones L, Forty L, Gordon-Smith K, Robertson-Blackmore E, Heron J, Craddock N, Jones I (2014). Perinatal mood disorders and parity – a clue to the aetiology of the postpartum trigger. Journal of Affective Disorders. 152-154; 334-339.

Forty L, Ulanova A, Jones L, Jones I, Gordon-Smith K, Fraser C, Farmer A, McGuffin P, Lewis C, Hosang G, Craddock N (2014). Comorbid Medical Illness in Bipolar Disorder. British Journal of Psychiatry. 205(6); 465-472.

 

External responsibilities

Katherine has presented her research at numerous national and international conferences. She regularly presents research findings and updates at research meetings and to healthcare professionals and patient support groups.

She is a review editor for Frontiers in Psychiatry: Mood and Anxiety Disorders.

Katherine is a peer reviewer for the academic journals Bipolar Disorders, Journal of Affective disorders, Frontiers in Psychiatry and the British Journal of Psychiatry.