Dr Steve O'Hickey

Research Team

M.B. Ch.B,   M.R.C.P.,    M.D.,      F.R.C.P,  F.A.A.A.A.I.

Consultant Physician in General Internal and Respiratory medicine, Worcester Royal Infirmary
Honorary Professor at the University of Worcester
Special interests include Allergy and Immunotherapy and Pulmonary Rehabilitation.  

After qualifying from Manchester Medical School in 1981 and residency in the Professorial Unit at Manchester Royal Infirmary, his early training posts were at Blackburn Royal Infirmary.   He was trained in Respiratory Medicine by Professor Peter Ormerod at Blackburn where he gained his membership of the Royal College of Physicians (M.R.C.P.).  

Post membership Dr O'Hickey worked in the Regional Infectious Diseases department at East Birmingham Hospital, 1994,  and then became Registrar in Cardiothoracic Medicine in the North Western Cardiothoracic Centre at Wythenshawe Hospital working for Professor C.A.C. Pickering, Dr. P.Barber and Dr. A. Hilton.  

Subsequently, he moved to the Department of Allergy and Allied Respiratory Diseases at Guy’s Hospital London in 1986 and spent 3 years as a Research Fellow to Professor Tak Lee in Allergy and Respiratory medicine.  

On completion of his M.D. thesis on exercise induced asthma and hypertonic airway challenge, he moved to Heartlands Hospital, Birmingham, as Senior Registrar in Respiratory and General Medicine, working for 4 years and rotating through all departments.  In particular he worked with Professor Sherwood Burge whose main interest was occupational lung disease and Professor Jon Ayres whose interest was in brittle asthma.  

After completion of his training, Dr O'Hickey became a Consultant Physician in Respiratory and General Medicine at Solihull Hospital in October 1993 where he started a bee and wasp venom desensitisation clinic.  He remained there until the summer of 1997 and since then he has been a Consultant Physician in Respiratory and General Medicine at the Chest Clinic, Worcestershire Royal Hospital.  

His main areas of interest include allergy and immunotherapy and end stage respiratory disease, in particular COPD and pulmonary rehabilitation for patients with chronic respiratory disease. 


Chairman of 3 Counties Lung Cancer NSSG 2006-2009 

Assistant Clinical Director of Medicine 2005-2009 

Clinical Lead for Respiratory Medicine 2003- present                                     

Lead Lung Cancer Physician 2004- present                                     

Clinical Director of R & D 1999 - 2004   

Research Interests

Since 1986 Dr O'Hickey has published a large number of papers in peer-reviewed journals, including papers on asthma, respiratory disease and occupational lung disease.   His research interests continue to be into chronic Allergy and respiratory disease. He has supervised a PhD student in motivation and quality of life in pulmonary rehabilitation.     

Pharmaceutical Trials: He has been involved in a large number of National and Multi-National trials into respiratory therapies including the Symbiosis Trial and ALK 23 immunotherapy trial.  



Pulmonary function and respiratory symptoms in a population of airport workers. Tunnicliffe WS.  O'Hickey SP.  Fletcher TJ.  Miles JF.  Burge PS.  Ayres JG. Occup Environ Med 1999;56:118-123.    

Occupational asthma due to chrome and nickel electroplating. Bright P.  Burge PS.  O'Hickey SP.  Gannon PF.  Robertson AS.  Boran A. Thorax.  52(1):28-32, 1997 Jan.    

Outcome for patients colonised with Burkholderia cepacia in a Birmingham adult cystic fibrosis clinic and the end of an epidemic. Muhdi K.  Edenborough FP.  Gumery L.  O'Hickey S.  Smith EG.  Smith DL.  Stableforth DE. Thorax.  51(4):374-7, 1996 Apr.    

Occupational asthma due to glutaraldehyde and formaldehyde in endoscopy and x ray departments. Gannon PF.  Bright P.  Campbell M.  O'Hickey SP.  Burge PS. Thorax.  50(2):156-9, 1995 Feb.    

Does single dose salmeterol affect exercise capacity in asthmatic men?. Robertson W.  Simkins J.  O'Hickey SP.  Freeman S.  Cayton RM. European Respiratory Journal.  7(11):1978-84, 1994 Nov.    

High-dose nedocromil sodium as an addition to inhaled corticosteroids in the treatment of asthma. O'Hickey SP.  Rees PJ. Respiratory Medicine.  88(7):499-502, 1994 Aug.    

Life-threatening right ventricular thrombosis in association with phospholipid antibodies. O'Hickey S.  Skinner C.  Beattie J. British Heart Journal.  70(3):279-81, 1993 Sep.    

Unusual spinal tuberculosis after adequate chemotherapy for lymph node tuberculosis in an immunocompetent man. O'Hickey SP.  Pithie A.  Skinner C. Thorax.  47(11):986-7, 1992 Nov. [UI: 1465762        

The effects of indomethacin on the refractory period to hypertonic saline-induced bronchoconstriction. Hawksworth RJ.  O'Hickey SP.  Lee TH. European Respiratory Journal.  5(8):963-6, 1992 Sep.      

Leukotrienes C4, D4, and E4 enhance histamine responsiveness in asthmatic airways. O'Hickey SP.  Hawksworth RJ.  Fong CY.  Arm JP.  Spur BW.  Lee TH. American Review of Respiratory Disease.  144(5):1053-7, 1991 Nov.      

Sulphidopeptide leukotrienes in asthma. [Review] [9 refs] Lee TH.  O'Hickey SP.  Jacques C.  Hawksworth RJ.  Arm JP.  Christie P.  Spur BW.  Crea AE. Advances in Prostaglandin, Thromboxane, & Leukotriene Research.  21A:415-9, 1991.    

Asthmatic airways have a disproportionate hyperresponsiveness to LTE4, as compared with normal airways, but not to LTC4, LTD4, methacholine, and histamine. Arm JP.  O'Hickey SP.  Hawksworth RJ.  Fong CY.  Crea AE.  Spur BW.  Lee TH. American Review of Respiratory Disease.  142(5):1112-8, 1990 Nov.    

Airway responsiveness to adenosine 5' monophosphate following inhalation of hypertonic saline. O'Hickey SP.  Rees PJ.  Lee TH. European Respiratory Journal.  2(10):923-8, 1989 Nov.      

Role of histamine release in hypertonic saline induced bronchoconstriction. O'Hickey SP.  Belcher NG.  Rees PJ.  Lee TH. Thorax.  44(8):650-3, 1989 Aug.    

Airway responsiveness to histamine and leukotriene E4 in subjects with aspirin-induced asthma. Arm JP.  O'Hickey SP.  Spur BW.  Lee TH. American Review of Respiratory Disease.  140(1):148-53, 1989 Jul.    

Exercise-induced asthma and late phase reactions. [Review] [30 refs] Lee TH.  O'Hickey SP. European Respiratory Journal.  2(3):195-7, 1989 Mar.    

Airway responsiveness to methacholine after inhalation of nebulized hypertonic saline in bronchial asthma. O'Hickey SP.  Arm JP.  Rees PJ.  Lee TH. Journal of Allergy & Clinical Immunology.  83(2 Pt 1):472-6, 1989 Feb.    

The relative responsiveness to inhaled leukotriene E4, methacholine and histamine in normal and asthmatic subjects. O'Hickey SP.  Arm JP.  Rees PJ.  Spur BW.  Lee TH. European Respiratory Journal.  1(10):913-7, 1988 Dec.    

Exercise induced rhinorrhoea. O'Hickey S.  Christie P.  Lee T. BMJ.  297(6657):1194-5, 1988 Nov 5. [Letter]    

Pathogenetic mechanisms of exercise-induced asthma and the refractory period. [Review] [21 refs] Belcher NG.  O'Hickey S.  Arm JP.  Lee TH. New England & Regional Allergy Proceedings.  9(3):199-201, 1988 May-Jun.    

Leukocytes and mediators in exercise induced asthma and hypertonic challenge to the airways. [Review] [24 refs] O'Hickey SP.  Arm JP.  Belcher NG.  Lee TH. Progress in Clinical & Biological Research.  263:341-53, 1988.    

Pathogenetic mechanisms of exercise induced asthma and the refractory period. [Review] [21 refs] Belcher NG.  O'Hickey S.  Arm JP.  Lee TH.    

Phaeochromocytoma associated with adult respiratory distress syndrome. O'Hickey S.  Hilton AM.  Whittaker JS. Thorax.  42(2):157-8, 1987 Feb.     24.       Fibreoptic bronchoscopy in the elderly. O'Hickey S.  Hilton AM. Age & Ageing.  16(4):229-33, 1987 Jul.

Manchester air disaster. O'Hickey SP.  Pickering CA.  Jones PE.  Evans JD. British Medical Journal Clinical Research Ed..  294(6588):1663-7, 1987 Jun 27.