Dr Claire Martin

claire martin

Senior Lecturer in Biomedical Sciences

Biological Sciences

Contact Details

email: c.martin@worc.ac.uk
tel: 01905 54 2982

Research Gate

Dr. Claire Martin (BSc Hons, PG Dip, FHEA, PhD, FRSB, CBiol), is a highly experienced biological scientist with an established track record of high quality national and international research, income generation, publications, presentations and industrial collaborations.

Claire read BSc (Hons) Neuroscience at the University of Sussex, followed by a PG Dip Biochemical Engineering at University College London (UCL).  After completing her PhD in pharmaceutical science at The University of London, School of Pharmacy (ULSOP), she developed key research themes of novel homogenisation strategies for biopharmaceutical products during a BBSRC-funded postdoctoral fellowship at ULSOP and University of Cambridge.

Claire started her academic career at the University of Wolverhampton, supporting the establishment and continuing development of the MPharm, BSc and MSc Pharmaceutical science programs. Claire joined the University of Worcester in 2018 and continues to pursue research interests centred around the development of responsive controlled release delivery systems for wound management, formulation and assay development of novel antimicrobial agents as well as development of non-parenteral formulations for the delivery of anti-infective agent.

Claire an active member of the academic pharmaceutical sciences community both nationally and internationally through collaborations, external examining and professional networking.  She is author/co-author of over 70 peer-reviewed publications, including journal articles, book chapters, reviews and conference proceedings as well as an active reviewer for numerous high impact pharmaceutical and analytical science journals, national funding bodies and international conference committees. Her contribution to the biological sciences has been recognised by the Royal Society of Biology with the award of Fellowship (FRSB) and granting of Chartered Biologist status (CBiol).

Qualifications

  • PG Cert Learning & Teaching in HE, University of Wolverhampton (2007)
  • PhD Pharmaceutical Science, University of London (2004)
  • PG Dip Biochemical Engineering, University College London (1999)
  • BSc (Hons) Neuroscience, University of Sussex (1998)

 

RESEARCH

  • Environmentally responsive, controlled release delivery systems for wound management
  • Formulation and assay development of novel antimicrobial agents
  • In vitro modelling of wound healing
  • Development of platform solid dosage formulation technologies combined with advanced drug delivery systems for the treatment of oropharyngeal and gastrointestinal infections

 

PUBLICATIONS

PUBLICATIONS

 

Journal Articles

  1. El-Ani, E., Martin, C., Britland, S.T., Doudin, K. and Hill, D.J. The effect of the morphology of hydroxypropyl methylcellulose particles and the ratio of a non-ionic polymer surfactant (Poloxamer 407) on chlorhexidine mucoadhesive buccal tablets.  Saudi Pharmaceutical Journal.  https://doi.org/10.1016/j.jsps.2019.04.012.
  2. Gupta, A., Keddie, D.J., Kannappan, V., Gibson, H., Khalil, I., Kowalczuk, M., Martin, C., Shuai, X. and Radecka, I. (2019). Production and characterisation of bacterial cellulose hydrogels loaded with curcumin encapsulated in cyclodextrins as wound dressings.  European Polymer Journal, 118: 437-450.
  3. Gupta, A., Kowalczuk, M., Heaselgrave, W., Britland, S.T., Martin, C. and Radecka, I. (2019). Production and application of hydrogels in wound management: A review.  European Polymer Journal, 111: 134 – 151.
  4. Wansi, J.D., Sewald, N., Nahar, L., Martin, C. and Sarker, S.D. (2019). Bioactive essential oils from the Cameroonian rain forest: A review - Part II.  Trends in Phytochemical Research, 3 (1): 3 – 52.
  5. Wansi, J.D., Sewald, N., Nahar, L., Martin, C. and Sarker, S.D. (2018). Bioactive essential oils from the Cameroonian rain forest: A review - Part I.  Trends in Phytochemical Research, 2 (4): 187 – 234.
  6. Mohamad, N., Amin, M.C.I.M., Martin, C. and Buang, F. Characterization and biocompatibility of bacterial cellulose-based wound dressing hydrogel: The effect of electron beam irradiation doses and concentrations of acrylic acid.  Journal of Biomedical Materials Research Part B: Applied Biomaterials, 105 (8): 2553 – 2564.
  7. Tahsin, T., Wansi, J.D., Al-Groshi, A., Evans, A., Nahar, L., Martin, C. and Sarker, S.D. (2017). Cytotoxic properties of the stem bark of Citrus reticulata Blanco (Rutaceae).  Phytotherapy Research, 31 (8): 1215 – 1219.
  8. Low, W.L., Kenward, M.A., Britland, S.T., Amin, M.C.I.M. and Martin, C. (2017). Essential oils and metal ions as alternative antimicrobial agents: A focus on tea tree oil and silver.  International Wound Journal, 14 (2): 369 – 384.
  9. Pandey, M., Mohamad, N., Martin, C. and Mohd Amin, M.C.I. (2017). Microwaved Bacterial Cellulose-Based Hydrogel Microparticles for the Healing of Partial Thickness Burn Wounds. Drug Delivery and Translational Research, 7 (1): 89 – 99.
  10. Gupta, A., Low, W.L., Radecka, I., Britland, S.T., Amin, C.I.M., and Martin, C. (2016). Characterisation and in vitro antimicrobial activity of biosynthetic silver-loaded bacterial cellulose hydrogels. Journal of Microencapsulation, 33 (8): 725 – 734.
  11. Wansi, J.D., Alain, T.T., Toze, F.A.A., Nahar, L., Martin, C. and Sarker, S.D. (2016). Cytotoxicity of Acridone and Idoloquinazoline Alkaloids from Zanthoxylum poggei. Phytochemistry Letters, 17: 293-298.
  12. Martin, C., Low, W.L., Gupta, A., Amin, M.C.I.M., Radecka, I., Britland, S.T., Raj, P. and Kenward, M.A. (2015). Strategies for Antimicrobial Drug Delivery to the Biofilm. Current Pharmaceutical Design, 21 (1): 43-66. 
  13. Wansi, J.D., Wandji, J., Sewald, N., Nahar, L., Martin, C. and Sarker, S.D. (2016). Phytochemistry and pharmacology of the genus Drypetes: A review. Journal of Ethnopharmacology, 190: 328 – 353.
  14. Low, W.L., Kenward, M.A., Amin, M.C.I.M. and Martin, C. (2016). Ionically crosslinked chitosan hydrogels for antimicrobial essential oils and metal ions delivery to enhance current wound management strategies. Medicines, 3 (1): Article 8 (DOI: 10.3390/medicines3010008).
  15. Low, W.L., Hill, D.J., Kenward, M.A. and Martin, C. (2016). Characterisation and in vitro Antimicrobial Potential of Liposome Encapsulated Silver Ions against Candida albicans. Journal of Microencapsulation, 33 (2): 146 – 152.
  16. Abeer, M.M., Amin, M.C.I.M. and Martin, C. (2014). A Review of Bacterial Cellulose-Based Drug Delivery Systems: Their Biochemistry, Current Approaches and Future Prospects. Journal of Pharmacy and Pharmacology, 66 (8): 1047 – 1061. 
  17. Abeer, M.M., Amin, C.I.M., Lazim, A.M., Pandey, M. and Martin, C. (2014). Synthesis of a Novel Acrylated Abietic Acid-g-Bacterial Cellulose Hydrogel by Gamma Irradiation. Carbohydrate Polymers, 110: 505 – 512. 
  18. Low, W.L., Martin, C., Hill, D.J. and Kenward, M.A. (2013). Antimicrobial Efficacy of Liposome Encapsulated Silver Ions and Tea Tree Oil Against Pseudomonas aeruginosa, Staphylococcus aureus and Candida albicans. Letters in Applied Microbiology, 57 (1): 33 – 39.
  19. Martin, C., Low, W.L., Amin, M.C.I.M., Radecka, I., Raj, P. and Kenward, M.A. (2013). Current trends in the development of wound dressings, biomaterials and devices. Pharmaceutical Patent Analyst, 2 (3): 341 – 359.
  20. Low, W.L., Martin, C., Hill, D.J. and Kenward, M.A. (2011). Antimicrobial Efficacy of Silver Ions in Combination with Tea Tree Oil Against Pseudomonas aeruginosa, Staphylococcus aureus and Candida albicans. International Journal of Antimicrobial Agents, 37 (2): 162 –
  21. Martin, C. (2009). Recent Developments in Wound Management: Intelligent Biomaterials to Novel Antimicrobials. Investigational Drugs, 12 (11): 695 –
  22. Martin, C., Somavarapu, S., and Alpar, H.O. (2005). Mucosal Delivery of Diphtheria Toxoid using Polymer Coated-Bioadhesive Liposomes as Vaccine Carriers. Journal of Drug Delivery Science and Technology, 15 (4): 301 – 306.
  23. Pandit, S., Martin, C. and Alpar, H.O. (2005). Positively Charged Rifampicin-Loaded Microspheres for Lung Delivery. Journal of Drug Delivery Science and Technology, 15 (4): 281 – 287.
  24. Martin, C., Thongborisute, J., Takeuchi, H., Yamamoto, H., Kawashima, Y. and Alpar, H.O. (2005). Cholesterol-Bile Salt Constructs as Potential Vehicles for Oral Delivery of Drugs and Vaccines. International Journal of Pharmaceutics, 298 (2): 339 – 343.

 

Book Chapters

  1. Radecka, I., Martin, C., Hill, D.J. (2015). “The Problem of Microbial Drug Resistance” in Novel Antimicrobial Agents and Strategies edited by Phoenix, D.A., Harris, F. and Dennison, S.R.  Wiley-VCH, Weinheim.  ISBN 978-3-527-33638-8.
  2. Martin, C., Low, W.L., Gupta, A., Amin, M.C.I.M., Radecka, I., Britland, S.T., Raj, P., and Kenward, M.A. (2014). “Liposomal Delivery of Antimicrobials” in Advances in Liposome Research (part of the Biochemistry Research Trends series) edited by Laura Finney.  Nova Science Publishers Inc., New York.  ISBN 978-1-63117-074-4.

 

Conference Abstracts

  1. Gupta, A., Kowalczuk, M., Martin, C. and Radecka, (2018). Biosynthetic cellulose based hydrogels of curcumin encapsulated in cyclodextrins as wound dressings.  Polish Society for Biomaterial’s 4th International Conference on Biomedical Polymers & Polymeric Biomaterials Proceedings, 15th-18th July, AGH University of Science and Technology, Kraków, Poland.
  2. Gupta, A., Kowalczuk, M., Martin, C. and Radecka, (2018). Biosynthetic hydrogels with curcumin-cyclodextrins Inclusion complex for wound management application.  Institute of Macromolecular Chemistry’s “10th Career in Polymers 2018Proceedings, 22nd-23rd June 2018, Institute of Macromolecular Chemistry, Czech Academy of Sciences, Prague, Czech Republic.
  3. Gupta, A., Low, W.L., Britland, S.T., Radecka, I and Martin, C. (2017). Physicochemical characterisation of biosynthetic bacterial cellulose as a potential wound dressing material.  British Journal of Pharmacy, 2(2): S37-38.
  4. Al-Ani, E., Hill, D.J., Britland, S.T. and Martin, C. (2017). An insight into understanding chlorhexidine release from hydrogel muco-adhesive buccal tablets using conventional and novel dissolution methods.  Joint Pharmaceutical Analysis Group (JPAG): “The pharmaceutical analysis postgraduate research awards and careers symposium” Proceedings, 28th November 2017, RSC, Burlington House, London, U.K.
  5. Al-Ani, E., Hill, D.J., Britland, ST. and Martin, C. (2017). Effect of Poloxamer 407 (P407) on the release of Chlorhexidine (CHX) from mucoadhesive buccal tablet.  UKPharmSci 2017 Conference Proceedings, 5th – 7th September 2017, De Havilland Campus, University of Hertfordshire, Hatfield, U.K. 
  6. Gupta, A., Low, W.L., Britland, S.T., Radecka, I. and Martin, C. (2017). Physicochemical characterisation of biosynthetic bacterial cellulose as a potential wound dressing material.  UKPharmSci 2017 Conference Proceedings 5th – 7th September 2017, De Havilland Campus, University of Hertfordshire, Hatfield, U.K. 
  7. Rai, P., Radecka, I., Britland, S.T. and Martin, C. (2017). Antimicrobial activity of silver-loaded bacterial cellulose hydrogels against Pseudomonas aeruginosa and Staphylococcus aureus: Effect of Hydration.  UKPharmSci 2017 Conference Proceedings, 5th – 7th September 2017, De Havilland Campus, University of Hertfordshire, Hatfield, U.K. 
  8. Buba, F., Low, W.L., Britland, S.T., Buratai, L. and Martin, C. (2017). Evaluation of maltodextrin as a lyoprotectant for the production of Taraba honey powder by freeze drying.  Analytical Biosciences Early Career Researcher Meeting, 15th – 16th March 2017, University of Warwick, Coventry, U.K. 
  9. Al-Ani, E., Hill, D.J., Britland, S.T. and Martin, C. (2017). Mucoadhesive buccal tablets for sustained release of chlorhexidine: Exploring the use of HPMC and Poloxamer 407 (P407) as hydrogel-forming polymers.  “Dissolution Testing: Current and Future Considerations” - A Joint Pharmaceutical Analysis Group Event, Royal Society of Chemistry, London, U.K.
  10. Gupta, A., Britland, S.T., Radecka, I. and Martin, C. (2016). Antimicrobial silver nanoparticle-loaded Bacterial cellulose hydrogels: Wound Management Applications. Chemistry: The Science Around Us Proceedings, 9th September 2016, University of Sheffield, Sheffield, U.K.  #13.
  11. Gupta, A., Britland, S.T., Radecka, I., Low, W.L. and Martin, C. (2016). Improved antimicrobial activity of silver nanoparticle-loaded bacterial cellulose hydrogels. UKPharmSci 2016 Conference Proceedings, 5th – 7th September 2016, Technology & Innovation Centre, University of Strathclyde, Glasgow, K. 
  12. Gupta, A., Britland, S.T., Radecka, I. and Martin, C. (2016). In vitro, quantitative study of the antimicrobial activity of nanoparticulate silver encapsulated in biosynthetic bacterial cellulose hydrogels. Emerging Analytical Professionals 2016 event proceedings, 13th – 15th May 2016, Solent Hotel & Spa, Fareham, U.K.
  13. Dosanjh, P.K., Low, W.L., Radecka, I., Britland, S.T. and Martin, C. (2015). Liposomal silver nitrate embedded within a bacterial cellulose hydrogel: Antimicrobial activity against Pseudomonas aeruginosa and Staphylococcus aureusLiposome Advances 2015 Conference Proceedings, 19th – 22nd December 2015, UCL School of Pharmacy, University of London, London, U.K.
  14. Gupta, A., Britland, S.T., Radecka, I. and Martin, C. (2015). The application of silver zeolite-loaded biosynthetic hydrogels for enhanced wound management. UKPharmSci 2015 Conference Proceedings, 6th – 8th September 2015, East Midlands Conference Centre, University of Nottingham, Nottingham, U.K. 
  15. Dosanjh, P.K., Gupta, A., Britland, S.T., Radecka, I. and Martin, C. (2015). The antimicrobial activity of silver zeolite loaded bacterial cellulose hydrogels against Staphylococcus aureus and Pseudomonas aeruginosa. Proceedings of the International Symposium of Controlled Release and Bioactive Materials, 42 (2015).  #977.
  16. Kainth, J.S., Grewal, A.S., Greenwood, S., Low, W.L., Kenward, M.A. and Martin, C. (2011). Controlled Release Chitosan Hydrogels for Delivery of Antimicrobials: I. Formation and Stability. UKPharmSci 2011 Conference Proceedings, 31st August – 2nd September 2011, East Midlands Conference Centre, University of Nottingham, Nottingham, U.K.
  17. Kainth, J.S., Grewal, A.S., Greenwood, S., Low, W.L., Kenward, M.A. and Martin, C. (2011). Controlled Release Chitosan Hydrogels for Delivery of Antimicrobials: II. Drug Release and Antimicrobial Activity. UKPharmSci 2011 Conference Proceedings, 31st August – 2nd September 2011, East Midlands Conference Centre, University of Nottingham, Nottingham, U.K.
  18. Low, W.L., Martin, C. and Kenward, M.A. (2011). Development of Antimicrobial Liposome Encapsulated Tea Tree Oil (TTO) and Silver Ions (Ag+) for Topical Wound Management. UKPharmSci 2011 Conference Proceedings, 31st August – 2nd September 2011, East Midlands Conference Centre, University of Nottingham, Nottingham, U.K.
  19. Low, W.L., Martin, C. and Kenward, M.A. (2010). Antimicrobial Activity of Zeolite Exchanged and Liposome Encapsulated Silver Ions. Proceedings of the International Symposium of Controlled Release and Bioactive Materials, 37 (2010).  #18.
  20. Low, W.L., Martin, C. and Kenward, M.A. (2010). Approaches to controlled release of antimicrobial tea tree oil (TTO) and silver ions (Ag+) by liposome encapsulation. Journal of Pharmacy and Pharmacology, 62 (10): 1250 – 1251.
  21. Rasul, N., Dosanjh, P.K., Hashmi, I., Abass, K., Riasat, U.A., Low, W.L., Kenward, M.A. and Martin, C. (2010). Ionically Crosslinked Chitosan Hydrogels for Controlled Release of Antibiotics. Proceedings of the International Symposium of Controlled Release and Bioactive Materials, 37 (2010).  #723.
  22. Low, W.L., Kenward, M.A. and Martin, C. (2009). Antimicrobial Effect of Tea Tree Oil and Silver: Potential Enhancement with Liposomal Encapsulation. Journal of Pharmacy and Pharmacology, 61: A-90, #122.
  23. Low, W.L., Martin, C. and Kenward, M.A. ‘Ken’ (2009). A comparison of antimicrobial efficacy of free and liposome encapsulated tea tree oil (TTO) and silver (AgNO3) both singly and in combination. Society for General Microbiology Spring Meeting Harrogate International Centre 30 March–2 April 2009.  Abstract number HAR2/04: 42.
  24. Martin, C., Bhujbal, U. and Kenward, M.A. (Ken) (2008). Antimicrobial Activity of Liposomal Tea Tree Oil and its Constituents. Journal of Pharmacy and Pharmacology, 60: A-45, #112.
  25. Martin, C., Bhujbal, U., and Kenward, M.A. (Ken) (2008). Controlled Release Formulation of Tea Tree Oil and its Constituents. Journal of Pharmacy and Pharmacology, 60: A-57, #145.
  26. Martin, C., O’Neill, J. and Chan, K. (2008). Interaction of Tea Tree Oil and its Constituents with Over-the-Counter Topical Medicines. Journal of Pharmacy and Pharmacology, 60: A-57, #144.
  27. Bhujbal, U., Kenward, M.A. (Ken) and Martin, C. (2008). Controlled Release Formulation of Liposomal Tea Tree Oil. Proceedings of the International Symposium of Controlled Release and Bioactive Materials, 35 (2008).  #739.
  28. Bhujbal, U., Kenward, M.A. (Ken) and Martin, C. (2008). Antimicrobial Activity of Controlled Release Liposomal Tea Tree Oil Formulations. Proceedings of the International Symposium of Controlled Release and Bioactive Materials, 35 (2008).  #729.
  29. Martin, C., Ross, C., Peacock, T. and Ward, K. (2008). Electrical Impedance Analysis of Tea Tree Oil Formulations: Stability in the Frozen State. Proceedings of the International Symposium of Controlled Release and Bioactive Materials, 35 (2008).  #917.
  30. O’Neill, J., Chan, K. and Martin, C. (2008). Interaction of Tea Tree Oil and its Constituents with Over-the-Counter Medicaments. Proceedings of the International Symposium of Controlled Release and Bioactive Materials, 35 (2008).  #376.
  31. Martin, C., Ross, C., Peacock, T. and Ward, K.R. (2007). Electrical Impedance Analysis of Nutraceutical Formulation Stability in the Frozen State. Journal of Pharmacy and Pharmacology, 59: A-3, #7. 
  32. Martin, C., Aery, S. Bhujbal, U., Hargun, N. and Kenward, M.A. (2007). Liposomal Delivery of Antimicrobial Natural Products. Journal of Pharmacy and Pharmacology, 59: A-19, #48.
  33. Martin, C., Ross, C., Peacock, T. and Ward, K.R. (2007). Electrical Impedance Analysis of Tea Tree Oil Formulations: Predicting Stability in the Frozen State. International Society for Lyophilisation and Freeze Drying (ISL-FD) Conference.  Dublin, Ireland.
  34. Martin, C., Ross, C., Peacock, T. and Ward, K.R. (2007). Application of Electrical Impedance Analysis for Investigation of Nutraceutical Formulation Stability in the Frozen State. Early Research Award Scheme Conference, University of Wolverhampton, U. K.
  35. Martin, C., Ross, C., Peacock, T. and Ward, K.R. (2007). Application of Electrical Impedance Analysis for Investigation of Nutraceutical Formulation Stability in the Frozen State. SET for Britain, presented at the House of Commons, London, Monday 19th March 2007: E2-28.
  36. Singh, R., Martin, C., Habinshuti, A.S., Brocchini, S. and Somavarapu, S. (2006). Microencapsulated Calcium-Phosphate and Chitosan Nanoparticles for Pulmonary Delivery of DNA. Journal of Pharmacy and Pharmacology, 58: S-191.
  37. Martin, C., Brocchini, S. Alpar, H.O. (2006). Preparation of Liposomes by Jet Homogenisation. Proceedings of the International Symposium of Controlled Release and Bioactive Materials, 33 (2006). # 723.
  38. Martin, C., Ingham, A.J., Ward, K.R. and Alpar, H.O. (2005). Application of Electrical Impedance Analysis for Investigation of Emulsion Stabilisers in the Frozen State. Journal of Pharmacy and Pharmacology, 57: S-68.
  39. Martin, C., Brocchini, S.B., Slater, N.K.H. and Alpar, H.O. (2004). Preparation of Polymeric Nanoparticles by Jet Homogenisation for Drug and Vaccine Delivery. Proceedings of the International Symposium of Controlled Release and Bioactive Materials, 31 (2004): # 605.
  40. Martin, C., Thongborisute, J., Takeuchi, H., Yamamoto, H., Kawashima, Y. and Alpar, H.O. (2003). Investigation of the Interactions between Cholesterol and Bile Salts. Proceedings of the International Symposium of Controlled Release and Bioactive Materials, 31 (2003): # 288.
  41. Martin, C., Atuah, K.N. and Alpar, H.O. (2002). Liposome-Alginic Acid Formulations for Oral Delivery: Stability in Gastrointestinal Fluids. Journal of Pharmacy and Pharmacology, 54: S40 – 41.
  42. Martin, C., Cocks, E.A. and Alpar, H.O. (2002). Effect of Freeze Drying on Vesicle Size, Aggregation and Entrapment for Liposomes Formulated with Poly(Vinyl Alcohol). Journal of Pharmacy and Pharmacology, 54: S77 – 78.
  43. Martin, C., Shah, K., Somavarapu, S. and Alpar, H.O. (2001). In Vitro Evaluation of Polymer-Coated Liposomes for Mucosal Delivery of Drugs and Vaccines. Proceedings of the International Symposium of Controlled Release and Bioactive Materials, 29 (2001): # 7021.
  44. Martin, C., Bramwell, V.W. and Alpar, H.O. (2000). Effect of Differential Time Point Addition of Sucrose on Liposome Characteristics During Freezing and Freeze Drying. Journal of Pharmacy and Pharmacology, 52 (suppl.): 29.

 

 

PROFESSIONAL BODIES & COMMITTEES

  • Athena SWAN, UK, Panellist (2014 – current)
  • Biochemical Society, UK, Member (2004 – Current)
  • Biology Education Research Group (BERG), UK, Member (2018 – Current)
  • British Pharmacology Society (BPS), Member (2018 – Current)
  • Institution of Chemical Engineers (IChemE), UK, Affiliate Member (1998 – Current)
  • Royal Society of Biology, UK, Fellow of the Royal Society of Biology (FRSB), Chartered Biologist (CBiol) (2010 – Current)
  • University of Worcester, College C Ethics Panel, Deputy Chair (2018 – Current)

UNDERGRADUATE TEACHING

First Year:

  • BIOS1010: Human Anatomy & Physiology
  • BIOS1201: Cell Biology
  • BIOS1203: Health and Disease (module leader)
  • BIOS1205: Introduction to Biological Chemistry
  • BIOS1400: Professional and Technical Development in Biomedical Science

Second Year:

  • BIOS2201: Molecular and Cellular Biology

Third Year:

  • BIOS3000: Independent Studies (project supervisor)
  • BIOS3106: Pharmacology
  • BIOS3400: Infection Science and Antimicrobial Resistance