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Sarah Knott

Research Associate in Psychological Medicine

Institute of Health & Society

Contact Details

email: s.knott@worc.ac.uk

tel: +44(0)1905 54 2802

Sarah Knott is a Research Associate in Psychological Medicine in the Institute of Health & Society.

Sarah is a member of the Mood Disorders Research Group. The broad aims of the group are to investigate genetic and other factors that may contribute to the aetiology of bipolar disorder and other related mood and psychotic illnesses, such as schizoaffective disorder and postpartum psychosis.

Sarah qualified with a first class BSc (Hons) in Psychology from Cardiff University in 2008. Following graduation, she worked within an adult acute psychiatric unit for a number of years before studying for an MSc in Health Psychology at the University of Wales Institute, Cardiff (now Cardiff Metropolitan University). Here Sarah developed an interest into the study of eating disorders, where her research focused on evaluating outcomes associated with cognitive behavioural therapy for individuals with bulimia nervosa and atypical eating disorders. She was awarded her Master’s degree with Distinction in 2011 and following this went on to work as a Research Officer, where she first began working with the Mood Disorders Research Group. During this time Sarah assisted in the coordination of mental health research across Wales and was responsible for the recruitment of individuals with bipolar disorder into the Bipolar Disorder Research Network (BDRN).

Sarah commenced her PhD at Cardiff University within the Institute of Psychological Medicine and Clinical Neurosciences in 2012 and plans to submit her PhD thesis in 2016. In October 2015, Sarah joined the University of Worcester as a Research Associate to continue her work with the Mood Disorders Research Group.

Qualifications

• Currently undertaking a PhD in Psychological Medicine at Cardiff University.
• 2011 MSc Health Psychology: Distinction, University of Wales Institute.
• 2008 BSc (Hons) Psychology: First Class, Cardiff University.

Research

Research

Sarah’s research interests lie in the aetiology of major mental illnesses, in particular bipolar disorder, postpartum psychosis, major unipolar depression and psychosis. Her principle research interest is the clinical phenotype of bipolar affective disorder and she has a particular interest in the medical comorbidity in affective disorder. In 2012, Sarah commenced a PhD exploring the relationship between bipolar disorder and the neurological disorders migraine and epilepsy. Co-occurring conditions within bipolar disorder can cause further complications and so it is hoped that a better understanding of the relationship between these disorders could have many implications for diagnosis, management and treatment.

Sarah is a member of the Mood Disorders Research Group and the Bipolar Disorder Research Network (BDRN). BDRN is a UK research programme founded by the Mood Disorders Research Group to investigate the underlying causes of bipolar disorder. BDRN has successfully recruited over 6100 participants and is the largest well-characterised cohort of individuals with bipolar disorder in the world to date and has detailed clinical, psychological, social and genetic data on all participants.

Sarah is currently involved in the recruitment of BDRN participants to take part in the mood monitoring system True Colours. This exciting and innovative new mood monitoring system is currently being offered to BDRN members, in collaboration with colleagues at the University of Oxford as part of CoNBRIO – Collaborative Network for Bipolar Research to Improve Outcomes. True Colours is an easy-to-use online technology that enables individuals to monitor their mood prospectively. The system will deliver groundbreaking data to help understand more about how mood symptoms present over time in individuals with bipolar disorder and how they are affected by changes in routines such as sleep.

Teaching

Teaching

Sarah enjoys teaching students about aspects of psychological medicine and has been involved in delivering seminars to medical undergraduates, encouraging them to gain experience and an understanding of psychiatric research.

Sarah has also been involved in the training of field team researchers in the areas of affective disorders and the use of psychiatric research assessment tools.

Memberships

Memberships

Bipolar Disorder Research Network

International Society of Psychiatric Genetics

Publications

Publications

Publications

S Knott, L Forty, N Craddock, RH Thomas (2015) Epilepsy and Bipolar Disorder. Epilepsy & Behavior, Epub ahead of print.
Gordon-Smith K, Forty L, Chan C, Knott S, Jones I, Craddock N and Jones LA (2015) Rapid cycling as a feature of bipolar disorder and comorbid migraine. Journal of Affective Disorders 175:320-4.

S Knott, I Jones, L Jones, K Gordon-Smith, L Forty, N Craddock (2015) Examining migraine in bipolar disorder. Bipolar Disorders, 17: 73.

S Knott, D Woodward, A Hoefkens, C Limbert (2014) Cognitive behaviour therapy for bulimia nervosa and eating disorders not otherwise specified: translation from randomized controlled trial to a clinical setting. Behavioural and Cognitive Psychotherapy 43(6):641-54.

Conference Presentations

S Knott, I Jones, L Jones, K Gordon-Smith, L Forty, N Craddock (2015). Examining migraine in bipolar disorder. Poster presentation at International Society for Bipolar Disorders, Toronto, June 2015.
S Knott, L Forty, I Jones, K Gordon-Smith, L Jones, N Craddock (2014). Phenotypic and Genetic Overlap in Bipolar Disorder and Migraine. Poster presentation at World Congress of Psychiatric Genetics, Copenhagen, October 2014.
S Knott, M Kerr, L Forty, I Jones, K Gordon-Smith, L Jones, N Craddock (2014). Epilepsy & bipolar disorder. Expert led oral presentation at ILAE British Chapter Annual Scientific Meeting, Nottingham, September 2014.
S Knott, L Forty, L Jones, I Jones, K Gordon-Smith, C Fraser, N Craddock (2013). Examining migraine in bipolar disorder. Poster presentation at Welsh Psychiatric Society & Royal College of Psychiatrists ‘New Advances’ conference, Swansea, May 2014.
S Knott, L Forty, L Jones, I Jones, K Gordon-Smith, C Fraser, N Craddock (2013). Investigating susceptibility to bipolar disorder and migraine. Poster presentation at Cardiff & Vale UHB Mental Health R&D meeting, Cardiff, December 2013.
S Knott, L Forty, L Jones, I Jones, K Gordon-Smith, C Fraser, N Craddock (2013). Investigating genetic susceptibility to bipolar disorder, migraine and epilepsy. Poster presentation at North Wales Mental Health & Learning Disabilities Research Conference, Bangor, May 2013 (Joint first prize in poster competition).
S Knott, L Forty, L Jones, I Jones, K Gordon-Smith, C Fraser, N Craddock (2013). Investigating genetic susceptibility to bipolar disorder, migraine and epilepsy. Poster presentation at Mental Health Research Network Cymru, Wrexham, March 2013 (First prize in poster competition).